Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991428 | 1.00 | GRM5 (0.47) | GRM5NPC1RAB9A | |
| SCHEMBL3664219 | 0.92 | GRM5 (0.41) | GRM5NPC1RAB9A | |
| SCHEMBL991434 | 0.90 | GRM5 (0.45) | GRM5NPC1RAB9A | |
| SCHEMBL990758 | 0.90 | GRM5 (0.45) | GRM5NPC1RAB9A | |
| SCHEMBL990890 | 0.89 | GRM5 (0.47) | GRM5 | |
| SCHEMBL990768 | 0.89 | GRM5 (0.47) | GRM5 | |
| SCHEMBL991105 | 0.84 | ALDH1A1 (0.48) | GRM5 | |
| SCHEMBL990050 | 0.84 | ALDH1A1 (0.48) | GRM5 | |
| SCHEMBL990750 | 0.83 | GRM5 (0.56) | GRM5 | |
| SCHEMBL14717873 | 0.81 | GRM5 (0.46) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |