Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | FABP4 | P15090 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptanoate SCHEMBL1131028 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL1131494 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL5552240 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL1131716 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL1132344 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL11331214 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL1131707 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL1131264 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL1131199 | 0.98 | AKR1B1 (0.64) | GPR84PPARGPPARDPPARAHDAC11 | |
| Valeric Acid SCHEMBL1131524 | 0.92 | AKR1B1 (0.54) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105013392-A | Easily biodegraded organosilicon surfactant and preparation method thereof | UNIV GUANGZHOU | 2015-11-04 | — | — | CN | claimed |
| US-10723670-B2 | Blasting compositions | Dyno Nobel Asia Pacific Pty Limited (AU) | 2020-07-28 | — | — | US | disclosed |
| CN-107793554-A | A kind of high-weatherability composite epoxy resin | 徐伟权 | 2018-03-13 | — | — | CN | disclosed |
| CN-105013392-A | Easily biodegraded organosilicon surfactant and preparation method thereof | UNIV GUANGZHOU | 2015-11-04 | — | — | CN | disclosed |
| CN-105013392-A | Easily biodegraded organosilicon surfactant and preparation method thereof | UNIV GUANGZHOU | 2015-11-04 | — | — | CN | disclosed |
| US-8883712-B2 | Fabric softening composition | EVONIK DEGUSSA GMBH (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20140311634-A1 | BLASTING COMPOSITIONS | Dyno Nobel Asia Pacific Pty Limited (AU) | 2014-10-23 | — | — | US | disclosed |
| EP-2780302-A1 | BLASTING COMPOSITIONS | Dyno Nobel Asia Pacific Pty Limited (AU) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013071363-A1 | BLASTING COMPOSITIONS | DYNO NOBEL ASIA PACIFIC PTY LTD (AU) | 2013-05-23 | — | — | WO | disclosed |
| US-20130053299-A1 | Fabric Softening Composition | EVONIK DEGUSSA GMBH (DE) | 2013-02-28 | — | — | US | disclosed |