⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11005601 | 0.74 | — | — | |
| SCHEMBL11005604 | 0.74 | — | — | |
| SCHEMBL13865171 | 0.69 | — | — | |
| SCHEMBL20888882 | 0.67 | — | — | |
| SCHEMBL19261 | 0.65 | — | — | |
| SCHEMBL10939968 | 0.65 | — | — | |
| SCHEMBL22900469 | 0.65 | CA1 (0.34) | — | |
| SCHEMBL2007651 | 0.63 | — | — | |
| SCHEMBL10999304 | 0.61 | — | — | |
| SCHEMBL37690 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491009-B1 | CYCLOPENTANECARBOXAMIDE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-8614238-B2 | Cyclopentanecarboxamide derivatives, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-24 | — | — | US | disclosed |
| US-20130053412-A1 | Cyclopentanecarboxamide derivatives, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | US | disclosed |