SCHEMBL14719746

SCHEMBL14719746

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nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
PRKCA P17252 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7932630 0.80 TSHR (0.44) TSHR
SCHEMBL7932628 0.80 TSHR (0.44) TSHR
Ethylene Glycol SCHEMBL11207147 0.79 TSHR (0.40) TSHRPRKCA
SCHEMBL21879754 0.76 TSHR (0.40) TSHR
SCHEMBL3899122 0.71 TSHR (0.51) TSHR
SCHEMBL5611593 0.69 TSHR (0.53) TSHRPRKCA
SCHEMBL29558246 0.69 TSHR (0.53) TSHR
SCHEMBL5611605 0.69 TSHR (0.53) TSHRPRKCA
SCHEMBL29557799 0.69 TSHR (0.53) TSHR
SCHEMBL3980478 0.68 ALDH1A1 (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130049255-A1 RESIN MOLD ASAHI KASEI KABUSHIKI KAISHA (JP) 2013-02-28 US disclosed