Sugi Predict

Sugi Predict / Compounds / SCHEMBL14719863

SCHEMBL14719863

SCHEMBL14719863

O=C(O)CC[C@H](NC(=O)C[C@H](NC(=O)CCCNC(=O)OCc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 9/20 0.72
▸ HTT P42858 1/20 0.62
▸ BMP1 P13497 1/20 0.52
▸ CAPN1 P07384 1/20 0.51
▸ CAPN2 P17655 1/20 0.51
▸ SIRT2 Q8IXJ6 1/20 0.49
▸ SIRT1 Q96EB6 1/20 0.49
▸ MMP2 P08253 1/20 0.49
▸ MMP9 P14780 1/20 0.49
▸ CPB1 P15086 1/20 0.48
▸ CPB2 Q96IY4 1/20 0.48
▸ MME P08473 1/20 0.48
▸ ECE1 P42892 1/20 0.48
▸ PTGER4 P35408 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22712908 1.00 FOLH1 (0.72) FOLH1HTTBMP1CAPN1CAPN2
SCHEMBL14729437 1.00 FOLH1 (0.72) FOLH1HTTBMP1CAPN1CAPN2
SCHEMBL14729505 0.96 FOLH1 (0.72) FOLH1HTTSIRT2SIRT1MMP2
SCHEMBL22712857 0.96 FOLH1 (0.72) FOLH1HTTSIRT2SIRT1MMP2
SCHEMBL22712945 0.94 FOLH1 (0.68) FOLH1HTTSIRT2SIRT1MME
SCHEMBL14729465 0.94 FOLH1 (0.68) FOLH1HTTSIRT2SIRT1MME
SCHEMBL25195535 0.91 FOLH1 (0.78) FOLH1HTTSIRT2SIRT1MMP2
SCHEMBL25216970 0.91 FOLH1 (0.78) FOLH1HTTSIRT2SIRT1MMP2
SCHEMBL29072085 0.88 FOLH1 (0.76) FOLH1HTTSIRT2SIRT1MMP2
SCHEMBL29072081 0.88 FOLH1 (0.76) FOLH1HTTSIRT2SIRT1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 — — US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 — — US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 — — US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 — — US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 — — US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 — — WO disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 FOLH1 4/4885HTT 2996/4885BMP1 380/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 FOLH1 4/4885HTT 2550/4885BMP1 393/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885HTT 4490/4885BMP1 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.