Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | BMP1 | P13497 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729437 | 1.00 | FOLH1 (0.72) | FOLH1HTTBMP1CAPN1CAPN2 | |
| SCHEMBL14719863 | 1.00 | FOLH1 (0.72) | FOLH1HTTBMP1CAPN1CAPN2 | |
| SCHEMBL14729505 | 0.96 | FOLH1 (0.72) | FOLH1HTTSIRT2SIRT1MMP2 | |
| SCHEMBL22712857 | 0.96 | FOLH1 (0.72) | FOLH1HTTSIRT2SIRT1MMP2 | |
| SCHEMBL22712945 | 0.94 | FOLH1 (0.68) | FOLH1HTTSIRT2SIRT1MME | |
| SCHEMBL14729465 | 0.94 | FOLH1 (0.68) | FOLH1HTTSIRT2SIRT1MME | |
| SCHEMBL25195535 | 0.91 | FOLH1 (0.78) | FOLH1HTTSIRT2SIRT1MMP2 | |
| SCHEMBL25216970 | 0.91 | FOLH1 (0.78) | FOLH1HTTSIRT2SIRT1MMP2 | |
| SCHEMBL29072085 | 0.88 | FOLH1 (0.76) | FOLH1HTTSIRT2SIRT1MMP2 | |
| SCHEMBL29072081 | 0.88 | FOLH1 (0.76) | FOLH1HTTSIRT2SIRT1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425547-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2024-12-26 | — | — | US | disclosed |
| US-12122851-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2024-10-22 | — | — | US | disclosed |
| US-10894807-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2021-01-19 | — | — | US | disclosed |
| US-20200377549-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425547-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885HTT 4490/4885BMP1 741/4885 |
| US-10894807-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885HTT 4490/4885BMP1 741/4885 |
| US-20200377549-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885HTT 4490/4885BMP1 741/4885 |
| US-12122851-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885HTT 4490/4885BMP1 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.