Sugi Predict

Sugi Predict / Compounds / SCHEMBL14720091

SCHEMBL14720091

SCHEMBL14720091

CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(N)=S)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 7/20 0.43
▸ ATM Q13315 2/20 0.41
▸ FOLH1 Q04609 2/20 0.41
▸ NPSR1 Q6W5P4 6/20 0.40
▸ MEN1 O00255 4/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ POLB P06746 3/20 0.40
▸ MAPT P10636 4/20 0.39
▸ P2RY12 Q9H244 2/20 0.38
▸ EPHX2 P34913 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ PAX8 Q06710 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ CA1 P00915 2/20 0.36
▸ CA2 P00918 2/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14720092 1.00 TDP1 (0.43) TDP1ATMFOLH1NPSR1MEN1
SCHEMBL22736959 0.88 TDP1 (0.43) TDP1ATMFOLH1NPSR1MEN1
SCHEMBL25963705 0.87 TDP1 (0.43) TDP1ATMFOLH1NPSR1MEN1
SCHEMBL30337966 0.87 FOLH1 (0.55) TDP1ATMFOLH1NPSR1MEN1
SCHEMBL25963701 0.87 FOLH1 (0.55) TDP1ATMFOLH1NPSR1MEN1
SCHEMBL22518777 0.87 TDP1 (0.54) TDP1ATMNPSR1MEN1KMT2A
SCHEMBL17701139 0.87 TDP1 (0.54) TDP1ATMNPSR1MEN1KMT2A
SCHEMBL20341481 0.86 TDP1 (0.43) TDP1ATMFOLH1NPSR1MEN1
SCHEMBL20341538 0.86 TDP1 (0.43) TDP1ATMFOLH1NPSR1MEN1
SCHEMBL23786252 0.85 TDP1 (0.43) TDP1ATMFOLH1NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 — — US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 — — US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 — — US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 — — US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 — — US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 TDP1 3245/4885ATM 2762/4885FOLH1 4/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 TDP1 3379/4885ATM 2042/4885FOLH1 4/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 TDP1 2960/4885ATM 1557/4885FOLH1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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