Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337966 | 0.88 | FOLH1 (0.55) | TDP1ATMFOLH1MAPTNPSR1 | |
| SCHEMBL17701139 | 0.88 | TDP1 (0.54) | TDP1ATMMAPTNPSR1MEN1 | |
| SCHEMBL25963701 | 0.88 | FOLH1 (0.55) | TDP1ATMFOLH1MAPTNPSR1 | |
| SCHEMBL22518777 | 0.88 | TDP1 (0.54) | TDP1ATMMAPTNPSR1MEN1 | |
| SCHEMBL4320228 | 0.86 | TDP1 (0.41) | TDP1ATMFOLH1MAPTNPSR1 | |
| SCHEMBL25963705 | 0.86 | TDP1 (0.43) | TDP1ATMFOLH1MAPTNPSR1 | |
| SCHEMBL22736959 | 0.85 | TDP1 (0.43) | TDP1ATMFOLH1MAPTNPSR1 | |
| SCHEMBL14720091 | 0.85 | TDP1 (0.43) | TDP1ATMFOLH1MAPTNPSR1 | |
| SCHEMBL20341481 | 0.85 | TDP1 (0.43) | TDP1ATMFOLH1MAPTNPSR1 | |
| SCHEMBL20341538 | 0.85 | TDP1 (0.43) | TDP1ATMFOLH1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827624-B2 | Covalent immune recruiter compounds for immune cell recognition and associated uses | MCMASTER UNIVERSITY (CA) | 2023-11-28 | — | — | US | disclosed |
| US-20210276981-A1 | COVALENT IMMUNE RECRUITER COMPOUNDS FOR IMMUNE CELL RECOGNITION AND ASSOCIATED USES | MCMASTER UNIVERSITY (CA) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827624-B2 | Covalent immune recruiter compounds for immune cell recognition and associated uses | CD74, CD4, HLA-A | TDP1 4226/4885EPHX1 2643/4885ATM 815/4885 |
| US-20210276981-A1 | COVALENT IMMUNE RECRUITER COMPOUNDS FOR IMMUNE CELL RECOGNITION AND ASSOCIATED USES | CD74, CD4, HLA-A | TDP1 4323/4885EPHX1 2334/4885ATM 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.