Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | CYCS | P99999 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702610 | 0.84 | STAT3 (0.50) | STAT3STAT1 | |
| SCHEMBL7259660 | 0.83 | STAT3 (0.64) | STAT3STAT1ENPP2TERTTOP1 | |
| SCHEMBL1290623 | 0.82 | STAT3 (0.56) | STAT3STAT1TERTTOP1CYCS | |
| SCHEMBL6744593 | 0.81 | STAT3 (0.55) | STAT3STAT1 | |
| SCHEMBL17112278 | 0.81 | STAT3 (0.55) | STAT3STAT1TERTTOP1CYCS | |
| SCHEMBL30831215 | 0.81 | STAT3 (0.53) | STAT3STAT1 | |
| SCHEMBL9641446 | 0.81 | STAT3 (0.44) | STAT3STAT1ENPP2 | |
| SCHEMBL9764318 | 0.81 | STAT3 (0.58) | STAT3STAT1 | |
| SCHEMBL5013624 | 0.80 | STAT3 (0.57) | STAT3STAT1ENPP2TERTTOP1 | |
| SCHEMBL19206150 | 0.80 | STAT3 (0.53) | STAT3STAT1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-08-14 | — | — | US | claimed |
| EP-2744771-B1 | C-HALOGEN BOND FORMATION | UNIV PRINCETON (US) | 2020-10-21 | — | — | EP | disclosed |
| US-20190127311-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-05-02 | — | — | US | disclosed |
| US-20160264512-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015054476-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20150031768-A1 | C-HALOGEN BOND FORMATION | NATIONAL SCIENCE FOUNDATION | 2015-01-29 | — | — | US | disclosed |
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-08-14 | — | — | US | disclosed |
| EP-2744771-A1 | C-HALOGEN BOND FORMATION | The Trustees of Princeton University (US) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013081685-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-06-06 | — | — | WO | disclosed |
| WO-2013028639-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | STAT3 2970/4885STAT1 4679/4885ENPP2 4428/4885 |
| US-20160264512-A1 | C-HALOGEN BOND FORMATION | FOS, BCL3, CBR3 | STAT3 3786/4885STAT1 4836/4885ENPP2 4364/4885 |
| US-20190127311-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | STAT3 2970/4885STAT1 4679/4885ENPP2 4428/4885 |
| US-20150031768-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | STAT3 2970/4885STAT1 4679/4885ENPP2 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.