Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | EBP | Q15125 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 3/20 | 0.34 |
| ▸ | CDC25B | P30305 | 3/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15298489 | 0.83 | MAPT (0.40) | LMNAMAPTEBPSIGMAR1BLM | |
| SCHEMBL15298586 | 0.83 | MAPT (0.40) | LMNAMAPTEBPSIGMAR1BLM | |
| SCHEMBL24370409 | 0.78 | LMNA (0.48) | LMNAMAPTEBPSIGMAR1BLM | |
| SCHEMBL11372817 | 0.77 | LMNA (0.56) | LMNAMAPTEBPSIGMAR1BLM | |
| SCHEMBL12501741 | 0.76 | MAPT (0.49) | LMNAMAPTEBPSIGMAR1BLM | |
| SCHEMBL15298491 | 0.76 | LMNA (0.46) | LMNAMAPTSIGMAR1BLMPTPN1 | |
| SCHEMBL876348 | 0.76 | — | — | |
| SCHEMBL4258397 | 0.74 | MAPT (0.33) | MAPTEBPCDC25ACDC25B | |
| SCHEMBL11454241 | 0.74 | CDC25A (0.31) | MAPTEBPCDC25ACDC25B | |
| SCHEMBL15298484 | 0.74 | LMNA (0.43) | LMNAMAPTSIGMAR1BLMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028307-A1 | DERIVATIVES OF HYDROCARBON TERPENES | Amyris, Inc. (US) | 2013-02-28 | — | — | WO | disclosed |