Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026186 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL7195917 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL28365668 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL2230706 | 0.95 | KDM4E (0.47) | KDM4EALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL7462976 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL7463633 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL16968739 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1HTTMEN1CYP3A4 | |
| SCHEMBL16968734 | 0.86 | KDM4E (0.37) | KDM4EALDH1A1MEN1CYP3A4CYP2C9 | |
| SCHEMBL28977621 | 0.86 | CA1 (0.42) | — | |
| SCHEMBL34809 | 0.85 | ALDH1A1 (0.40) | KDM4EALDH1A1HTTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9631101-B2 | Ionic liquid release coat for use in metal flake manufacture | ECKART AMERICA CORPORATION (US) | 2017-04-25 | — | — | US | claimed |
| US-20140350147-A1 | IONIC LIQUID RELEASE COAT FOR USE IN METAL FLAKE MANUFACTURE | ECKART AMERICA CORPORATION (US) | 2014-11-27 | — | — | US | claimed |
| EP-2747918-A1 | IONIC LIQUID RELEASE COAT FOR USE IN METAL FLAKE MANUFACTURE | Eckart America Corporation (US) | 2014-07-02 | — | — | EP | claimed |
| WO-2013028970-A1 | IONIC LIQUID RELEASE COAT FOR USE IN METAL FLAKE MANUFACTURE | ECKART AMERICA CORPORATION (US) | 2013-02-28 | — | — | WO | claimed |
| US-9631101-B2 | Ionic liquid release coat for use in metal flake manufacture | ECKART AMERICA CORPORATION (US) | 2017-04-25 | — | — | US | disclosed |
| US-20140350147-A1 | IONIC LIQUID RELEASE COAT FOR USE IN METAL FLAKE MANUFACTURE | ECKART AMERICA CORPORATION (US) | 2014-11-27 | — | — | US | disclosed |
| EP-2747918-A1 | IONIC LIQUID RELEASE COAT FOR USE IN METAL FLAKE MANUFACTURE | Eckart America Corporation (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013028970-A1 | IONIC LIQUID RELEASE COAT FOR USE IN METAL FLAKE MANUFACTURE | ECKART AMERICA CORPORATION (US) | 2013-02-28 | — | — | WO | disclosed |