Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12497730 | 0.89 | NR1H2 (0.42) | KMT2AMEN1ALDH1A1L3MBTL1ESR2 | |
| SCHEMBL14720680 | 0.86 | SRD5A2 (0.44) | KMT2AMEN1ALDH1A1L3MBTL1SRD5A2 | |
| SCHEMBL1602307 | 0.82 | OGA (0.46) | KMT2AMEN1ALDH1A1PKMNR1H2 | |
| SCHEMBL6392515 | 0.81 | GRM5 (0.45) | KMT2AMEN1ESR2PKMNR1H2 | |
| SCHEMBL29902983 | 0.80 | KMT2A (0.52) | KMT2AMEN1ALDH1A1L3MBTL1NR1H2 | |
| SCHEMBL10306695 | 0.80 | KMT2A (0.52) | KMT2AMEN1ALDH1A1L3MBTL1NR1H2 | |
| SCHEMBL7971750 | 0.80 | ESR2 (0.48) | KMT2AMEN1ALDH1A1ESR2NR1H2 | |
| SCHEMBL20304926 | 0.79 | KMT2A (0.46) | KMT2AMEN1ALDH1A1PKMNR1H2 | |
| SCHEMBL20333548 | 0.79 | KMT2A (0.46) | KMT2AMEN1ALDH1A1PKMNR1H2 | |
| SCHEMBL20304927 | 0.79 | KMT2A (0.46) | KMT2AMEN1ALDH1A1PKMNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |