Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.73 |
| ▸ | CES1 | P23141 | 12/20 | 0.73 |
| ▸ | FAAH2 | Q6GMR7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471174 | 0.85 | FAAH (0.71) | FAAHCES1FAAH2 | |
| SCHEMBL1471243 | 0.84 | FAAH (1.00) | FAAHCES1FAAH2 | |
| SCHEMBL1471635 | 0.83 | FAAH (0.73) | FAAHCES1FAAH2 | |
| SCHEMBL1472135 | 0.82 | FAAH (0.73) | FAAHCES1FAAH2 | |
| SCHEMBL1471208 | 0.77 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1474087 | 0.77 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1471575 | 0.76 | FAAH (0.72) | FAAHCES1 | |
| SCHEMBL1471400 | 0.75 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1474042 | 0.75 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1472013 | 0.75 | FAAH (0.72) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | claimed |