Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720855 | 0.91 | POLB (0.40) | KMT2AMEN1POLBALDH1A1HTT | |
| SCHEMBL14720457 | 0.79 | HRH3 (0.33) | ALDH1A1 | |
| SCHEMBL14720732 | 0.79 | CYP2C19 (0.41) | KMT2AMEN1POLBALDH1A1HTT | |
| SCHEMBL14720551 | 0.79 | ALDH1A1 (0.56) | POLBALDH1A1HTTNPC1RAB9A | |
| SCHEMBL14720880 | 0.78 | POLB (0.34) | POLBPKMLMNAMAPT | |
| SCHEMBL12697262 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1POLBALDH1A1HTT | |
| SCHEMBL14720812 | 0.78 | HRH3 (0.34) | — | |
| SCHEMBL14721332 | 0.77 | HRH3 (0.39) | KMT2AMEN1 | |
| SCHEMBL14720541 | 0.77 | POLB (0.43) | KMT2AMEN1POLBALDH1A1PKM | |
| SCHEMBL14720724 | 0.76 | ALDH1A1 (0.58) | KMT2APOLBALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |