Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720504 | 0.97 | HRH3 (0.35) | HRH3SRD5A2POLBL3MBTL3 | |
| SCHEMBL14720505 | 0.97 | HRH3 (0.35) | HRH3SRD5A2POLBL3MBTL3 | |
| SCHEMBL14720667 | 0.93 | SRD5A2 (0.34) | HRH3SRD5A2POLB | |
| SCHEMBL14720924 | 0.91 | SRD5A2 (0.38) | HRH3SRD5A2POLB | |
| SCHEMBL14720798 | 0.89 | SRD5A2 (0.32) | SRD5A2 | |
| SCHEMBL14720674 | 0.87 | SRD5A2 (0.30) | SRD5A2 | |
| SCHEMBL14720789 | 0.86 | HRH3 (0.37) | HRH3SRD5A2POLBL3MBTL3 | |
| SCHEMBL14720612 | 0.86 | HRH3 (0.35) | HRH3SRD5A2POLBL3MBTL3 | |
| SCHEMBL14720727 | 0.85 | HRH3 (0.36) | HRH3 | |
| SCHEMBL14720597 | 0.84 | POLB (0.38) | HRH3SRD5A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |