SCHEMBL14721005

SCHEMBL14721005

CCOC(=O)COc1ccc(Br)c(OCC(=O)OCC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.56
ALDH1A1 P00352 5/20 0.56
NPSR1 Q6W5P4 2/20 0.56
MAPT P10636 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP3A4 P08684 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
LMNA P02545 1/20 0.56
NTSR1 P30989 1/20 0.56
GAA P10253 5/20 0.55
KDM4E B2RXH2 5/20 0.55
HSD17B10 Q99714 3/20 0.55
TSHR P16473 1/20 0.50
PTPN1 P18031 3/20 0.48
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8428121 0.91 PTPN1 (0.55) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL27642525 0.86 SMN1; SMN2 (0.59) HPGDALDH1A1NPSR1MAPTLMNA
SCHEMBL22542315 0.84 HPGD (0.59) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL5531605 0.84 GAA (0.53) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL16569366 0.84 KDM4E (0.53) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL7038455 0.83 GAA (0.56) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL595665 0.82 GAA (0.52) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL3929739 0.82 PTPN1 (0.57) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL2013386 0.82 HPGD (0.56) HPGDALDH1A1NPSR1MAPTCYP1A2
SCHEMBL24478464 0.81 BRD4 (0.55) MAPTPTPN1SMN1; SMN2PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944657-B2 Luminescent lanthanide chelates having three chromophores an their use RADIOMETER TURKU OY (FI) 2018-04-17 US disclosed
EP-2794812-B1 NOVEL LUMINESCENT LANTHANIDE CHELATES WITH ENHANCED EXCITATION PROPERTIES RADIOMETER TURKU OY (FI) 2017-03-22 EP disclosed
US-9518186-B2 Luminescent lanthanide chelates with enhanced excitation properties RADIOMETER TURKU OY (FI) 2016-12-13 US disclosed
EP-2753674-B1 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2016-02-10 EP disclosed
US-20140017807-A9 NOVEL LUMINESCENT LANTHANIDE CHELATES WITH ENHANCED EXCITATION PROPERTIES DHR FINLAND OY (FI) 2014-01-16 US disclosed
US-20130210165-A1 Luminescent Lanthanide Chelates Having Three Chromophores and Their Use DHR FINLAND OY (FI) 2013-08-15 US disclosed
US-20130183771-A1 NOVEL LUMINESCENT LANTHANIDE CHELATES WITH ENHANCED EXCITATION PROPERTIES DHR FINLAND OY (FI) 2013-07-18 US disclosed
WO-2013026790-A9 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2013-05-23 WO disclosed
WO-2013026790-A1 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210165-A1 Luminescent Lanthanide Chelates Having Three Chromophores and Their Use GLB1, SSB, LGALS3BP HPGD 3124/4885ALDH1A1 3095/4885NPSR1 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.