SCHEMBL14722233

SCHEMBL14722233

FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(Br)=CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14729751 0.81
SCHEMBL14721704 0.74
SCHEMBL901820 0.73 CHRNA1 (0.36)
SCHEMBL1938040 0.73
SCHEMBL16013778 0.71
SCHEMBL14721916 0.70
SCHEMBL1935674 0.69
SCHEMBL16014040 0.68 AHR (0.34)
SCHEMBL14721621 0.68 CCR2 (0.30)
SCHEMBL2355523 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428741-B Cyclic compounds substituted by condensed ring systems 巴斯夫欧洲公司 2021-06-25 CN disclosed
EP-3237395-B1 CYCLIC COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM BASF SE (DE) 2019-08-07 EP disclosed
US-10023563-B2 Cyclic compounds substituted by a condensed ring system BASF SE (DE) 2018-07-17 US disclosed
US-20170369479-A1 CYCLIC COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM BASF SE (DE) 2017-12-28 US disclosed
US-20140343049-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-11-20 US disclosed
US-20140343049-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-11-20 US disclosed
US-20140343049-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-11-20 US disclosed
US-20140235533-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-08-21 US disclosed
US-20140235533-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-08-21 US disclosed
US-20140235533-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-08-21 US disclosed
EP-2748137-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2014-07-02 EP disclosed
WO-2013026724-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2013-02-28 WO disclosed
WO-2013026726-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2013-02-28 WO disclosed
WO-2013026724-A1 DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2013-02-28 WO disclosed