Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519123 | 0.88 | PDE10A (1.00) | PDE10AALDH1A1 | |
| SCHEMBL16627456 | 0.84 | PDE10A (0.80) | PDE10AALDH1A1 | |
| SCHEMBL518973 | 0.83 | PDE10A (0.79) | PDE10AALDH1A1 | |
| SCHEMBL518905 | 0.83 | PDE10A (0.79) | PDE10AALDH1A1 | |
| SCHEMBL19789841 | 0.82 | PDE10A (0.78) | PDE10AALDH1A1 | |
| SCHEMBL30123639 | 0.82 | PDE10A (0.79) | PDE10AALDH1A1 | |
| SCHEMBL15005246 | 0.82 | PDE10A (0.79) | PDE10AALDH1A1 | |
| SCHEMBL519127 | 0.82 | PDE10A (0.79) | PDE10AALDH1A1 | |
| SCHEMBL18399520 | 0.82 | PDE10A (0.80) | PDE10AALDH1A1 | |
| SCHEMBL519305 | 0.81 | PDE10A (0.76) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006031-A1 | PYRIDAZINONE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2016-04-13 | — | — | EP | disclosed |
| EP-2393360-B1 | PYRIDAZINONE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2015-11-04 | — | — | EP | disclosed |
| EP-2748158-A1 | RADIOLABELED COMPOUNDS AND THEIR USE AS RADIOTRACERS FOR QUANTITATIVE IMAGING OF PHOSPHODIESTERASE (PDE10A) IN MAMMALS | Takeda Pharmaceutical Company Limited (JP) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013027845-A1 | RADIOLABELED COMPOUNDS AND THEIR USE AS RADIOTRACERS FOR QUANTITATIVE IMAGING OF PHOSPHODIESTERASE (PDE10A) IN MAMMALS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |