Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478388 | 0.91 | PKM (0.58) | PKMMAPTRAB9ANPC1TDP1 | |
| SCHEMBL29362649 | 0.91 | PKM (0.58) | PKMMAPTRAB9ANPC1TDP1 | |
| SCHEMBL349628 | 0.91 | PKM (0.58) | PKMMAPTRAB9ANPC1TDP1 | |
| SCHEMBL173452 | 0.91 | PKM (0.58) | PKMMAPTRAB9ANPC1TDP1 | |
| SCHEMBL17142326 | 0.91 | PKM (0.58) | PKMMAPTRAB9ANPC1TDP1 | |
| SCHEMBL837337 | 0.91 | PKM (0.58) | PKMMAPTRAB9ANPC1TDP1 | |
| SCHEMBL409050 | 0.86 | CA12 (0.54) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL42286 | 0.86 | CA12 (0.54) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL29367675 | 0.86 | CA12 (0.54) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL42287 | 0.86 | CA12 (0.54) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748183-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | Universität Leipzig (DE) | 2014-07-02 | — | — | EP | claimed |
| WO-2013026927-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITÄT LEIPZIG (DE) | 2013-02-28 | — | — | WO | claimed |
| EP-2748183-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | Universität Leipzig (DE) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026927-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITÄT LEIPZIG (DE) | 2013-02-28 | — | — | WO | disclosed |