Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.39 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722945 | 0.92 | CSNK2A1 (0.47) | HTTKDM4ECSNK2A1BRD4MEN1 | |
| SCHEMBL17756314 | 0.82 | CSNK2A1 (0.47) | HTTKDM4ECSNK2A1BRD4MEN1 | |
| SCHEMBL21829032 | 0.81 | FOLH1 (0.48) | FOLH1TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL10779221 | 0.80 | CSNK2A1 (0.49) | POLBHTTKDM4ECSNK2A1BRD4 | |
| SCHEMBL9724906 | 0.79 | FOLH1 (0.49) | FOLH1POLBHTTKDM4ETSHR | |
| SCHEMBL7758673 | 0.79 | FOLH1 (0.49) | FOLH1HTTTSHRALDH1A1 | |
| SCHEMBL9724910 | 0.79 | FOLH1 (0.49) | FOLH1POLBHTTKDM4ETSHR | |
| SCHEMBL23269328 | 0.78 | CSNK2A1 (0.46) | POLBHTTKDM4ECSNK2A1BRD4 | |
| SCHEMBL15543860 | 0.78 | FOLH1 (0.48) | FOLH1HTTKDM4ETSHRALDH1A1 | |
| SCHEMBL5819855 | 0.78 | FOLH1 (0.48) | FOLH1HTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751061-A1 | UNSYMMETRICAL ALPHA, GAMMA-ALKYLENE-DI-P-TOLUATES, THE PRODUCTION THEREOF AND THEIR USE | Invista Technologies S.a r.l. (CH) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013026918-A1 | UNSYMMETRICAL Α,Γ-ALKYLENE-DI-P-TOLUATES, THE PRODUCTION THEREOF AND THEIR USE | INVISTA TECHNOLOGIES S.À.R.L (CH) | 2013-02-28 | — | — | WO | disclosed |