Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724906 | 1.00 | FOLH1 (0.49) | FOLH1CLCN2POLBALDH1A1ALOX15 | |
| SCHEMBL2578003 | 0.86 | FOLH1 (0.50) | FOLH1CLCN2POLBALDH1A1ALOX15 | |
| SCHEMBL29644540 | 0.86 | FOLH1 (0.50) | FOLH1CLCN2POLBALDH1A1ALOX15 | |
| SCHEMBL7758673 | 0.86 | FOLH1 (0.49) | FOLH1CLCN2ALDH1A1ALOX15TSHR | |
| SCHEMBL1552387 | 0.85 | HMGB1 (0.53) | FOLH1CLCN2POLBALDH1A1ALOX15 | |
| SCHEMBL8094022 | 0.84 | ALDH1A1 (0.40) | FOLH1CLCN2POLBALDH1A1ALOX15 | |
| SCHEMBL15543860 | 0.84 | FOLH1 (0.48) | FOLH1CLCN2ALDH1A1ALOX15TSHR | |
| SCHEMBL21829032 | 0.84 | FOLH1 (0.48) | FOLH1ALDH1A1ALOX15TSHRMEN1 | |
| SCHEMBL8085912 | 0.84 | KMT2A (0.39) | FOLH1CLCN2POLBALDH1A1TSHR | |
| SCHEMBL27700923 | 0.84 | IRAK4 (0.45) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100579-A | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0191600-B1 | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4911861-A | Mixture of at least two components | AJINOMOTO CO., INC. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4728458-A | FERROELECTRIC | AJINOMOTO CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0191600-A2 | Polyphenyl-based ester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4423212-A | Nucleosides and process | THE UPJOHN COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| US-4171431-A | Nucleosides and process | THE UPJOHN COMPANY (US) | 1979-10-16 | — | — | US | disclosed |