Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789422 | 0.85 | ELANE (0.50) | ELANESRD5A2GAAALDH1A1RAB9A | |
| SCHEMBL8373045 | 0.84 | ELANE (0.53) | ELANESRD5A2GAAALDH1A1RAB9A | |
| SCHEMBL478510 | 0.84 | KMT2A (0.63) | SRD5A2ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL7716884 | 0.83 | SMN1; SMN2 (0.58) | ELANESRD5A2SMN1; SMN2PPARA | |
| SCHEMBL29009109 | 0.83 | ELANE (0.59) | ELANESRD5A2GAAALDH1A1RAB9A | |
| SCHEMBL7611800 | 0.82 | ELANE (0.50) | ELANESRD5A2GAAALDH1A1RAB9A | |
| SCHEMBL8371946 | 0.82 | ELANE (0.50) | ELANESRD5A2GAAALDH1A1RAB9A | |
| SCHEMBL8375161 | 0.82 | ELANE (0.50) | ELANESRD5A2GAAALDH1A1RAB9A | |
| SCHEMBL1470281 | 0.81 | ELANE (0.53) | ELANESRD5A2GAAALDH1A1RAB9A | |
| SCHEMBL1534312 | 0.80 | KMT2A (0.69) | ELANESRD5A2GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296235-A1 | 1H-BENZIMIDAZOLE-4-CARBOXAMIDES SUBSTITUTED WITH PHENYL AT THE 2-POSITION ARE POTENT PARP INHIBITORS | ABBVIE INC. | 2014-10-02 | — | — | US | disclosed |
| EP-2744834-A1 | POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES | Lambson Limited (GB) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013026451-A1 | POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES | COLOPLAST A/S (DK) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296235-A1 | 1H-BENZIMIDAZOLE-4-CARBOXAMIDES SUBSTITUTED WITH PHENYL AT THE 2-POSITION ARE POTENT PARP INHIBITORS | PARP1, PARP2, PARP4 | ELANE 2118/4885SRD5A2 2464/4885GAA 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.