SCHEMBL3789422

SCHEMBL3789422

C=C(O)C(=O)OC(CC)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.50
L3MBTL1 Q9Y468 3/20 0.45
LMNA P02545 2/20 0.45
MAPK1 P28482 1/20 0.45
SRD5A2 P31213 1/20 0.43
ALDH1A1 P00352 4/20 0.43
RAB9A P51151 2/20 0.43
GAA P10253 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HTT P42858 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HPGD P15428 1/20 0.40
ABCB1 P08183 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14313368 0.89 MAPT (0.41) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL14723237 0.85 ELANE (0.58) ELANEL3MBTL1LMNAMAPK1SRD5A2
SCHEMBL3784684 0.83 CYP1A2 (0.40) ELANEL3MBTL1LMNAMAPK1ALDH1A1
SCHEMBL195096 0.80 KDM4E (0.43) LMNAALDH1A1RAB9AGAASMN1; SMN2
SCHEMBL1404301 0.79 MTNR1A (0.42) ELANEALDH1A1GAAMAPTPPARA
SCHEMBL2638606 0.78 HTT (0.50) ELANEL3MBTL1MAPK1SRD5A2ALDH1A1
SCHEMBL195237 0.78 MEN1 (0.37) LMNARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL4194206 0.77 HPGD (0.54) ELANEL3MBTL1LMNAMAPK1ALDH1A1
SCHEMBL6308376 0.75 ELANE (0.40) ELANEALDH1A1RAB9AGAASMN1; SMN2
SCHEMBL8373045 0.74 ELANE (0.53) ELANEL3MBTL1LMNAMAPK1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1371694-B1 Polymeric nanoparticle formulations and their use for improving the dirt pick up resistance of a coating ROHM & HAAS (US) 2010-03-03 EP claimed
US-7138438-B2 Polymeric nanoparticle formulations and their use for improving the dirt pick up resistance of a coating ROHM AND HAAS COMPANY (US) 2006-11-21 US claimed
US-20060217453-A1 POLYMERIC NANOPARTICLE FORMULATIONS AND THEIR USE FOR IMPROVING THE DIRT PICK UP RESISTANCE OF A COATING ROHM AND HAAS COMPANY 2006-09-28 US claimed
EP-1371694-A2 Polymeric nanoparticle formulations and their use for improving the dirt pick up resistance of a coating ROHM AND HAAS COMPANY (US) 2003-12-17 EP claimed
EP-1371690-A2 Polymeric nanoparticle formulations and their use in microbe repellent coatings ROHM AND HAAS COMPANY (US) 2003-12-17 EP claimed
US-11186726-B2 Aqueous polymer dispersion and aqueous coating composition comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2021-11-30 US disclosed
EP-3607013-B1 AQUEOUS POLYMER DISPERSION AND AQUEOUS COATING COMPOSITION COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-07-14 EP disclosed
US-20200048474-A1 AQUEOUS POLYMER DISPERSION AND AQUEOUS COATING COMPOSITION COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2020-02-13 US disclosed
EP-1371694-B1 Polymeric nanoparticle formulations and their use for improving the dirt pick up resistance of a coating ROHM & HAAS (US) 2010-03-03 EP disclosed
US-7138438-B2 Polymeric nanoparticle formulations and their use for improving the dirt pick up resistance of a coating ROHM AND HAAS COMPANY (US) 2006-11-21 US disclosed
US-20060217453-A1 POLYMERIC NANOPARTICLE FORMULATIONS AND THEIR USE FOR IMPROVING THE DIRT PICK UP RESISTANCE OF A COATING ROHM AND HAAS COMPANY 2006-09-28 US disclosed
EP-1371690-A2 Polymeric nanoparticle formulations and their use in microbe repellent coatings ROHM AND HAAS COMPANY (US) 2003-12-17 EP disclosed
EP-1371694-A2 Polymeric nanoparticle formulations and their use for improving the dirt pick up resistance of a coating ROHM AND HAAS COMPANY (US) 2003-12-17 EP disclosed