Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723289 | 0.86 | NAE1 (0.53) | NAE1UBA3 | |
| SCHEMBL14921589 | 0.85 | NAE1 (0.45) | NAE1UBA3 | |
| SCHEMBL14921588 | 0.84 | NAE1 (0.45) | NAE1UBA3 | |
| SCHEMBL14719846 | 0.83 | NAE1 (0.51) | NAE1UBA3 | |
| SCHEMBL14719844 | 0.83 | NAE1 (0.51) | NAE1UBA3 | |
| SCHEMBL14723085 | 0.82 | NAE1 (0.68) | NAE1UBA3 | |
| SCHEMBL14719789 | 0.82 | NAE1 (0.68) | NAE1UBA3 | |
| SCHEMBL15958749 | 0.82 | NAE1 (0.55) | NAE1UBA3 | |
| SCHEMBL29484028 | 0.82 | NAE1 (0.68) | NAE1UBA3 | |
| Hydrochloric Acid SCHEMBL14719845 | 0.82 | NAE1 (0.67) | NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748168-A2 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2014-07-02 | — | — | EP | claimed |
| WO-2013028832-A2 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-02-28 | — | — | WO | claimed |
| EP-2748168-A2 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013028832-A2 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-02-28 | — | — | WO | disclosed |