Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15025759 | 0.93 | NAE1 (0.51) | NAE1UBA3 | |
| SCHEMBL15024142 | 0.91 | NAE1 (0.52) | NAE1UBA3 | |
| SCHEMBL14719789 | 0.90 | NAE1 (0.68) | NAE1UBA3 | |
| SCHEMBL29484028 | 0.90 | NAE1 (0.68) | NAE1UBA3 | |
| SCHEMBL14723085 | 0.90 | NAE1 (0.68) | NAE1UBA3 | |
| Hydrochloric Acid SCHEMBL14719845 | 0.89 | NAE1 (0.67) | NAE1UBA3 | |
| SCHEMBL14723289 | 0.89 | NAE1 (0.53) | NAE1UBA3 | |
| SCHEMBL14719844 | 0.88 | NAE1 (0.51) | NAE1UBA3 | |
| SCHEMBL14719846 | 0.88 | NAE1 (0.51) | NAE1UBA3 | |
| SCHEMBL19749332 | 0.86 | NAE1 (0.57) | NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809356-B2 | Inhibitors of NEDD8-activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | disclosed |