Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 9/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723590 | 0.86 | GPR119 (0.40) | ALOX5APGPR119 | |
| SCHEMBL14723457 | 0.76 | KDM1A (0.39) | ALOX5APGPR119LMNAMAPT | |
| SCHEMBL12685457 | 0.75 | GPR119 (0.61) | GPR119 | |
| SCHEMBL14723294 | 0.70 | GPR119 (0.34) | GPR119 | |
| SCHEMBL12685447 | 0.68 | GPR119 (0.62) | GPR119 | |
| SCHEMBL8592327 | 0.67 | ALOX5AP (0.37) | ALOX5APGPR119 | |
| SCHEMBL15001098 | 0.66 | GPR119 (0.42) | ALOX5APGPR119 | |
| SCHEMBL470684 | 0.64 | GPR119 (0.47) | ALOX5APGPR119LMNAMAPT | |
| SCHEMBL8578929 | 0.63 | GPR119 (0.43) | ALOX5APGPR119 | |
| SCHEMBL12490078 | 0.63 | GPR119 (0.39) | ALOX5APGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |