Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10135393 | 0.95 | ELANE (0.37) | ELANENT5EKMT2AMEN1MAPT | |
| SCHEMBL10135414 | 0.94 | NT5E (0.37) | ELANENT5EKMT2AMEN1MAPT | |
| SCHEMBL10135416 | 0.90 | NT5E (0.43) | ELANENT5EKMT2AMEN1MAPT | |
| SCHEMBL13018972 | 0.89 | ELANE (0.48) | ELANEMAPTSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10181803 | 0.89 | NT5E (0.44) | ELANENT5EKMT2AMEN1MAPT | |
| SCHEMBL14723721 | 0.86 | ELANE (0.36) | ELANENT5EKMT2AMEN1MAPT | |
| SCHEMBL10135395 | 0.84 | ELANE (0.48) | ELANEMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL10135394 | 0.83 | ELANE (0.46) | ELANEMAPTSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL10183482 | 0.81 | NT5E (0.34) | ELANENT5EKMT2AMEN1MAPT | |
| SCHEMBL10181459 | 0.80 | ELANE (0.51) | ELANENT5EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383088-B2 | Coumestan-like antioxidants and UV absorbants | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |