SCHEMBL10135394

SCHEMBL10135394

CCCCCc1cc2oc3cc(O)c(C)cc3c2c(=O)o1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46
ALOX15 P16050 1/20 0.44
MAPT P10636 2/20 0.43
CNR2 P34972 4/20 0.42
CNR1 P21554 3/20 0.42
PGAM1 P18669 2/20 0.41
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10135395 0.99 ELANE (0.48) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL13018972 0.94 ELANE (0.48) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL10135398 0.92 ELANE (0.43) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL10182090 0.91 PGAM1 (0.49) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL10181459 0.90 ELANE (0.51) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL16167898 0.90 ELANE (0.51) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL10135420 0.90 ELANE (0.51) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL10135414 0.89 NT5E (0.37) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL10135393 0.88 ELANE (0.37) ELANEALDH1A1HTTSMN1; SMN2TP53
SCHEMBL14723717 0.85 MCL1 (0.39) ELANEALDH1A1HTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859235-B2 Methods in cell cultures, and related inventions, employing certain additives BASF SE (DE) 2014-10-14 US disclosed
US-8383088-B2 Coumestan-like antioxidants and UV absorbants BASF SE (DE) 2013-02-26 US disclosed
US-20120164162-A1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BASF SE (DE) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164162-A1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BBOX1, NEFM, NQO1 ELANE 509/4885ALDH1A1 152/4885HTT 1709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.