Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723928 | 0.79 | CNR2 (0.40) | CNR1CNR2HMGCRALDH1A1CYP1A2 | |
| SCHEMBL14724233 | 0.79 | CNR1 (0.40) | CNR1CNR2ALDH1A1KDM4ENPC1 | |
| SCHEMBL1012596 | 0.77 | CNR2 (0.39) | CNR1CNR2 | |
| SCHEMBL9891491 | 0.77 | CNR1 (0.39) | CNR1CNR2ALDH1A1MEN1MAPK1 | |
| SCHEMBL9892809 | 0.76 | CNR1 (0.39) | CNR1CNR2 | |
| SCHEMBL2609438 | 0.75 | ALDH1A1 (0.44) | CNR2ALDH1A1CYP1A2MEN1MAPK1 | |
| SCHEMBL9891817 | 0.74 | CNR2 (0.56) | CNR1CNR2ALDH1A1RAF1BRAF | |
| SCHEMBL10216934 | 0.72 | CNR2 (0.57) | CNR1CNR2ALDH1A1RAF1BRAF | |
| SCHEMBL1091042 | 0.72 | SMN1; SMN2 (0.38) | CNR1CNR2ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL12602876 | 0.72 | SMN1; SMN2 (0.36) | ALDH1A1CYP1A2MAPK1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |