Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31360528 | 0.85 | ABCB1 (0.70) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL16425629 | 0.84 | MEN1 (0.55) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL14535764 | 0.82 | ABCB1 (0.57) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL3503594 | 0.81 | MEN1 (0.72) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL14533580 | 0.81 | MEN1 (0.54) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL92964 | 0.78 | P2RY6 (0.49) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL14463386 | 0.76 | MEN1 (0.39) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL25933452 | 0.76 | P2RY6 (0.46) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL16425633 | 0.75 | MEN1 (0.49) | ABCB1ATMUSP2MEN1KMT2A | |
| SCHEMBL13848619 | 0.75 | ABCB1 (0.58) | ABCB1ATMUSP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383672-B2 | Halogenated rhodamine derivatives and applications thereof | KIADIS PHARMA CANADA INC. (NL) | 2013-02-26 | — | — | US | disclosed |