Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.42 |
| ▸ | PPOX | P50336 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.40 |
| ▸ | TACR3 | P29371 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639548 | 0.89 | CCR1 (0.47) | CCR1MAPTALDH1A1LMNASUV39H2 | |
| SCHEMBL1639550 | 0.89 | CCR1 (0.47) | CCR1MAPTALDH1A1LMNASUV39H2 | |
| SCHEMBL12765552 | 0.89 | CCR1 (0.47) | CCR1MAPTALDH1A1LMNASUV39H2 | |
| SCHEMBL3464356 | 0.81 | CCR1 (0.59) | CCR1 | |
| SCHEMBL3464357 | 0.81 | CCR1 (0.59) | CCR1 | |
| SCHEMBL4811812 | 0.80 | CXCR3 (0.50) | CCR1MAPTALDH1A1LMNASUV39H2 | |
| SCHEMBL13229276 | 0.79 | MAPT (0.44) | CCR1MAPTALDH1A1LMNAROCK2 | |
| SCHEMBL3859958 | 0.77 | CCR1 (0.66) | CCR1 | |
| SCHEMBL13869126 | 0.77 | CCR1 (0.48) | CCR1MAPTALDH1A1LMNASUV39H2 | |
| SCHEMBL13869125 | 0.77 | CCR1 (0.49) | CCR1SUV39H2ROCK2PRKG1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383630-B2 | Azaindazole compounds and methods of use | CHEMOCENTRYX, INC. (US) | 2013-02-26 | — | — | US | disclosed |