⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520517 | 0.75 | — | — | |
| SCHEMBL8268062 | 0.75 | — | — | |
| SCHEMBL1708582 | 0.75 | — | — | |
| Fluorouracil SCHEMBL592897 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL15772488 | 0.73 | NOS3 (0.36) | — | |
| SCHEMBL16225639 | 0.71 | — | — | |
| SCHEMBL15354442 | 0.71 | — | — | |
| SCHEMBL21359151 | 0.71 | — | — | |
| SCHEMBL12878591 | 0.71 | — | — | |
| SCHEMBL10726701 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122267-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| EP-2781512-B1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | UNIV SHANGHAI JIAOTONG (CN) | 2017-06-28 | — | — | EP | disclosed |
| US-9145405-B2 | Oxadiazole compound and preparation method thereof, pharmaceutical composition and use thereof | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-09-29 | — | — | US | disclosed |
| US-9145405-B2 | Oxadiazole compound and preparation method thereof, pharmaceutical composition and use thereof | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-09-29 | — | — | US | disclosed |
| US-20140350026-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) | 2014-11-27 | — | — | US | disclosed |
| US-20140350026-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) | 2014-11-27 | — | — | US | disclosed |
| EP-2781512-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Jiao Tong University (CN) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013071693-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海交通大学 (CN) | 2013-05-23 | — | — | WO | disclosed |
| EP-2562163-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562175-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562165-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562166-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |