Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950358 | 0.80 | SLC6A2 (0.50) | APOBEC3GKDM4EMAPK1EPHX1SLC6A2 | |
| SCHEMBL27946664 | 0.76 | KDM4E (0.57) | APOBEC3GKDM4EMAPK1IDO1ALDH1A1 | |
| SCHEMBL467713 | 0.76 | KDM4E (0.45) | APOBEC3GKDM4EMAPK1EPHX1SLC6A2 | |
| SCHEMBL17820 | 0.76 | IDO1 (0.57) | TSHRIDO1ALDH1A1TP53TAAR1 | |
| SCHEMBL30829273 | 0.76 | IDO1 (0.57) | TSHRIDO1ALDH1A1TP53TAAR1 | |
| SCHEMBL6278011 | 0.76 | APOBEC3G (0.43) | APOBEC3GKDM4EMAPK1EPHX1SLC6A2 | |
| SCHEMBL11001855 | 0.76 | APOBEC3G (0.43) | APOBEC3GKDM4EMAPK1EPHX1SLC6A2 | |
| SCHEMBL30065199 | 0.76 | APOBEC3G (0.43) | APOBEC3GKDM4EMAPK1EPHX1SLC6A2 | |
| SCHEMBL8053490 | 0.76 | RIPK1 (0.39) | APOBEC3GKDM4EMAPK1EPHX1SLC6A2 | |
| SCHEMBL17445915 | 0.74 | KDM4E (0.51) | KDM4EMAPK1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562175-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |