Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970879 | 0.81 | DNMT1 (0.55) | DNMT1ADRB1LMNASMN1; SMN2TP53 | |
| SCHEMBL12808873 | 0.81 | DNMT1 (0.55) | DNMT1ADRB1LMNASMN1; SMN2TP53 | |
| SCHEMBL17822560 | 0.78 | TLR7 (0.47) | DNMT1ADRB1LMNATP53HTT | |
| SCHEMBL6973748 | 0.78 | TLR7 (0.47) | DNMT1ADRB1LMNATP53HTT | |
| SCHEMBL18948312 | 0.72 | TLR7 (0.37) | DNMT1ADRB1TLR7 | |
| SCHEMBL24728914 | 0.72 | LMNA (0.53) | DNMT1LMNASMN1; SMN2TP53HTT | |
| SCHEMBL13845607 | 0.72 | LMNA (0.53) | DNMT1LMNASMN1; SMN2TP53HTT | |
| SCHEMBL14725002 | 0.72 | LMNA (0.53) | DNMT1LMNASMN1; SMN2TP53HTT | |
| SCHEMBL13272135 | 0.72 | LMNA (0.53) | DNMT1LMNASMN1; SMN2TP53HTT | |
| SCHEMBL510423 | 0.72 | LMNA (0.53) | DNMT1LMNASMN1; SMN2TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2561872-A1 | 3, 5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo [4,5-d]pyrimidin-2-one compounds and prodrugs thereof | Anadys Pharmaceuticals, Inc. (US) | 2013-02-27 | — | — | EP | disclosed |