SCHEMBL14724960

SCHEMBL14724960

CC(O)[C@H](Cn1c(=O)sc2c(=O)[nH]c(N)nc21)OC(CO)CO

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6983803 0.81 TLR7 (0.46) TLR7
SCHEMBL8434408 0.81 TLR7 (0.47) TLR7
SCHEMBL13851087 0.72 HPGD (0.51) TLR7
SCHEMBL22911663 0.72 TLR7 (0.44) TLR7
SCHEMBL8435465 0.71 PNP (0.61) TLR7
SCHEMBL8434599 0.71 TLR7 (0.45) TLR7
SCHEMBL13377792 0.70 PDE3A (0.49) TLR7
SCHEMBL22911735 0.70 TLR7 (0.53) TLR7
SCHEMBL8437308 0.69 TK1 (0.51) TLR7
SCHEMBL22911645 0.69 TLR7 (0.41) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2561872-A1 3, 5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo [4,5-d]pyrimidin-2-one compounds and prodrugs thereof Anadys Pharmaceuticals, Inc. (US) 2013-02-27 EP disclosed