Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970797 | 0.87 | TLR7 (0.41) | TLR7 | |
| SCHEMBL6973330 | 0.83 | KDM4E (0.43) | TLR7KMT2AMEN1 | |
| SCHEMBL338596 | 0.81 | TLR7 (0.41) | TLR7KMT2ACHRNA1CHRNB2CHRNA7 | |
| SCHEMBL14725008 | 0.81 | TLR7 (0.43) | TLR7KMT2AMEN1ATMGAA | |
| SCHEMBL27538529 | 0.71 | KMT2A (0.41) | TLR7KMT2ACHRNA1CHRNB2CHRNA7 | |
| SCHEMBL25539344 | 0.70 | CYP2C19 (0.33) | — | |
| SCHEMBL15295610 | 0.69 | — | — | |
| SCHEMBL15292864 | 0.69 | ALDH1A1 (0.53) | KMT2AMEN1GAAMAPT | |
| SCHEMBL6974590 | 0.69 | — | — | |
| SCHEMBL6974701 | 0.68 | TLR7 (0.41) | TLR7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2561872-A1 | 3, 5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo [4,5-d]pyrimidin-2-one compounds and prodrugs thereof | Anadys Pharmaceuticals, Inc. (US) | 2013-02-27 | — | — | EP | disclosed |