Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338450 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL339186 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL1313958 | 0.92 | ALDH1A1 (0.60) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL6976869 | 0.92 | ALDH1A1 (0.69) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL510895 | 0.92 | ALDH1A1 (0.69) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL12593016 | 0.92 | ALDH1A1 (0.69) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL6976500 | 0.87 | ALDH1A1 (0.64) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL12593023 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL510407 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TLR7LMNATHRBSMN1; SMN2 | |
| SCHEMBL6973892 | 0.85 | TLR7 (0.50) | ALDH1A1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2561872-A1 | 3, 5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo [4,5-d]pyrimidin-2-one compounds and prodrugs thereof | Anadys Pharmaceuticals, Inc. (US) | 2013-02-27 | — | — | EP | disclosed |