Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31616384 | 0.83 | IDH1 (0.54) | IDH1TRPV1EPHX2LMNAGAA | |
| SCHEMBL31616459 | 0.83 | IDH1 (0.69) | IDH1TRPV1EPHX2LMNAGAA | |
| SCHEMBL31616412 | 0.83 | IDH1 (0.54) | IDH1TRPV1EPHX2LMNAGAA | |
| SCHEMBL31616462 | 0.83 | IDH1 (0.69) | IDH1TRPV1EPHX2LMNAGAA | |
| SCHEMBL31616425 | 0.83 | IDH1 (0.54) | IDH1TRPV1EPHX2LMNAGAA | |
| SCHEMBL31616396 | 0.83 | IDH1 (0.69) | IDH1TRPV1EPHX2LMNAGAA | |
| SCHEMBL19377027 | 0.81 | IDH1 (0.58) | IDH1TRPV1EPHX2LMNA | |
| SCHEMBL31616465 | 0.81 | KMT2A (0.53) | IDH1TRPV1LMNA | |
| SCHEMBL31616452 | 0.81 | KMT2A (0.53) | IDH1TRPV1LMNA | |
| SCHEMBL31616458 | 0.81 | KMT2A (0.53) | IDH1TRPV1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITETET I OSLO (NO) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | CA9, CA2, CA4 | IDH1 70/4885TRPV1 860/4885EPHX2 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.