SCHEMBL14727672

SCHEMBL14727672

C=C(C)C(=O)Oc1ccc(C2(c3ccc(OC(=O)C(=C)C)cc3)CCC(C3CCC(CC)CC3)CC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
ATM Q13315 1/20 0.40
ELANE P08246 1/20 0.40
ADORA3 P0DMS8 1/20 0.35
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
CYP19A1 P11511 1/20 0.31
HPGD P15428 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727673 0.92 KMT2A (0.44) KMT2AATMELANEADORA3NFKB1
SCHEMBL14727711 0.91 THRB (0.37) KMT2AATMELANEADORA3NFKB1
SCHEMBL14727702 0.89 KMT2A (0.41) KMT2AATMELANEADORA3NFKB1
SCHEMBL14478762 0.89 KMT2A (0.36) KMT2AATMELANEADORA3HPGD
SCHEMBL14727682 0.88 KMT2A (0.36) KMT2AATMELANEADORA3HPGD
SCHEMBL16093596 0.88 KMT2A (0.42) KMT2AATMELANEADORA3NFKB1
SCHEMBL14727678 0.86 THRB (0.42) KMT2AATMELANEADORA3NFKB1
SCHEMBL14727697 0.84 THRB (0.34) KMT2AATMELANEADORA3HPGD
SCHEMBL14727681 0.84 KMT2A (0.40) KMT2AATMELANEADORA3HPGD
SCHEMBL14727686 0.84 THRB (0.42) KMT2AATMELANEADORA3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8840807-B2 Polymerizable compound JNC CORPORATION (JP) 2014-09-23 US disclosed
US-8840807-B2 Polymerizable compound JNC CORPORATION (JP) 2014-09-23 US disclosed
US-20130048912-A1 POLYMERIZABLE COMPOUND JNC PETROCHEMICAL CORPORATION (JP) 2013-02-28 US disclosed
US-20130048912-A1 POLYMERIZABLE COMPOUND JNC PETROCHEMICAL CORPORATION (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048912-A1 POLYMERIZABLE COMPOUND PYM1, ZYX, CPNE4 KMT2A 617/4885ATM 2670/4885ELANE 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.