SCHEMBL14728186

SCHEMBL14728186

c1ccc(N(c2ccc3c(c2)c2ccccc2c2cc4c(cc32)c2ccccc2n4-c2ccc3ccccc3c2)c2cccc3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
PRSS1 P07477 1/20 0.35
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PMM2 O15305 1/20 0.32
MPI P34949 1/20 0.32
PHOSPHO1 Q8TCT1 1/20 0.32
HPRT1 P00492 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728181 0.95 F2 (0.36) F2F10PRSS1KDM4EATM
SCHEMBL14728185 0.91 KDM4E (0.40) F2F10PRSS1KDM4EATM
SCHEMBL14728183 0.91 KDM4E (0.42) F2F10PRSS1KDM4EATM
SCHEMBL14728175 0.91 KDM4E (0.37) F2F10PRSS1KDM4EATM
SCHEMBL10029904 0.89 KDM4E (0.39) F2F10PRSS1KDM4EATM
SCHEMBL22302487 0.88 KDM4E (0.35) F2F10PRSS1KDM4EATM
SCHEMBL19383360 0.87 F2 (0.36) F2F10PRSS1KDM4EATM
SCHEMBL19342630 0.87 KDM4E (0.42) F2F10PRSS1KDM4EATM
SCHEMBL10029897 0.87 KDM4E (0.37) F2F10PRSS1KDM4EATM
SCHEMBL14728150 0.87 KDM4E (0.44) F2F10PRSS1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 F2 2977/4885F10 3451/4885PRSS1 3919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.