Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSB | P07858 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.52 |
| ▸ | ECE1 | P42892 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | CASP6 | P55212 | 2/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19523359 | 0.90 | CTSL (0.64) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL8199206 | 0.88 | ELANE (0.61) | CTSLCTSSCTSBCTSKATM | |
| SCHEMBL2978398 | 0.85 | CTSL (0.63) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL1287168 | 0.85 | CTSL (0.63) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL8671882 | 0.85 | CTSL (0.63) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL220569 | 0.85 | CTSL (0.63) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL20885259 | 0.85 | SYK (0.59) | CTSLCTSSCTSBCTSKATM | |
| SCHEMBL11657615 | 0.85 | SYK (0.59) | CTSLCTSSCTSBCTSKATM | |
| SCHEMBL1642698 | 0.85 | CTSL (0.52) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL12401100 | 0.85 | CYP3A4 (0.52) | CTSLCTSSCTSBCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053325-A1 | Secondary Structure Stabilized NMDA Receptor Modulators and Uses Thereof | INNOVIVA TRC HOLDINGS LLC | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053325-A1 | Secondary Structure Stabilized NMDA Receptor Modulators and Uses Thereof | GRIN2A, GRIN1, GRIN3A | CTSL 4593/4885CTSS 4529/4885CTSB 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.