Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQLE | Q14534 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051900 | 0.92 | SQLE (0.68) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL15975345 | 0.89 | SQLE (0.59) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL19850534 | 0.85 | SQLE (0.58) | SQLEKMT2AMAPTMEN1ALOX15 | |
| SCHEMBL8618707 | 0.84 | SQLE (0.81) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL8618704 | 0.84 | SQLE (0.81) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL6768879 | 0.84 | SQLE (0.81) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL6768881 | 0.84 | SQLE (0.81) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL8947231 | 0.82 | SQLE (0.78) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL8624130 | 0.82 | SQLE (0.78) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL9168757 | 0.82 | SQLE (0.78) | SQLEKMT2AMAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052301-A1 | CHEWING GUM COMPOSITIONS | WM. WRIGLEY JR. COMPANY | 2013-02-28 | — | — | US | disclosed |