SCHEMBL14729351

SCHEMBL14729351

O=C(CNOCc1ccccc1)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 1/20 0.47
ACE P12821 1/20 0.46
CCKBR P32239 3/20 0.43
MBTPS1 Q14703 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
MAPK1 P28482 1/20 0.42
TACR1 P25103 1/20 0.41
CASP1 P29466 2/20 0.41
POLB P06746 3/20 0.40
MAPT P10636 1/20 0.40
NOD2 Q9HC29 1/20 0.40
CDC25B P30305 1/20 0.40
FOLH1 Q04609 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825301 0.86 ACE (0.51) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL19401695 0.86 ACE (0.51) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL20322999 0.86 ACE (0.51) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL7716617 0.84 ACE (0.54) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL13296311 0.84 KMT2A (0.55) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL23446025 0.84 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL24235647 0.84 ACE (0.54) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL7717865 0.83 ACE (0.55) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL27387111 0.83 ACE (0.55) ALDH1A1MEN1KMT2AHPGDACE
SCHEMBL14102857 0.83 FOLH1 (0.54) ALDH1A1MEN1KMT2AHPGDACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 ALDH1A1 2393/4885MEN1 235/4885KMT2A 2592/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 ALDH1A1 2109/4885MEN1 197/4885KMT2A 2897/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 ALDH1A1 3049/4885MEN1 59/4885KMT2A 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.