Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529570 | 1.00 | SYK (0.81) | SYKJAK2 | |
| SCHEMBL14717914 | 1.00 | SYK (0.81) | SYKJAK2 | |
| SCHEMBL14717294 | 0.90 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL30604793 | 0.87 | SYK (0.69) | SYKJAK2 | |
| SCHEMBL14717049 | 0.86 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL29635081 | 0.86 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL14729762 | 0.86 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL29635121 | 0.85 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL14716887 | 0.85 | SYK (1.00) | SYKJAK2 | |
| SCHEMBL20376755 | 0.85 | SYK (0.67) | SYKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028818-A1 | PYRIMIDO- PYRIDAZINONE COMPOUNDS AND USE THEREOF | ENDO PHARMACEUTICALS INC. (US) | 2013-02-28 | — | — | WO | disclosed |