Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 15/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730236 | 0.95 | DPP4 (0.36) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730285 | 0.88 | DPP4 (0.43) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730288 | 0.88 | DPP4 (0.41) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730166 | 0.85 | RET (0.31) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730358 | 0.84 | DPP4 (0.37) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730357 | 0.83 | DPP4 (0.36) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730286 | 0.83 | GPR119 (0.37) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730238 | 0.82 | DPP4 (0.40) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730283 | 0.82 | DPP4 (0.40) | DPP4DPP7DPP8DPP9CYP2D6 | |
| SCHEMBL14730299 | 0.81 | DPP4 (0.37) | DPP4DPP7DPP8DPP9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |