Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064830 | 0.83 | GPR119 (0.41) | MCHR1GPR119KCNH2 | |
| SCHEMBL470604 | 0.81 | GPR119 (0.49) | MCHR1GPR119KCNH2 | |
| SCHEMBL14730363 | 0.81 | GPR119 (0.36) | GPR119KCNH2 | |
| SCHEMBL470653 | 0.81 | GPR119 (0.43) | MCHR1GPR119KCNH2 | |
| SCHEMBL14730364 | 0.81 | MCHR1 (0.40) | MCHR1HTR2ADRD3HTR7KDM1A | |
| SCHEMBL119963 | 0.80 | GPR119 (0.41) | MCHR1GPR119KCNH2 | |
| SCHEMBL470688 | 0.79 | GPR119 (0.46) | MCHR1GPR119KCNH2 | |
| SCHEMBL470555 | 0.79 | GPR119 (0.39) | MCHR1GPR119KCNH2 | |
| SCHEMBL14730361 | 0.78 | GPR119 (0.35) | GPR119KCNH2 | |
| SCHEMBL461833 | 0.78 | MCHR1 (0.36) | MCHR1HTR2AHTR7HTR1AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |