Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730373 | 0.88 | — | — | |
| SCHEMBL9856471 | 0.84 | TSHR (0.46) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL9856475 | 0.84 | TSHR (0.46) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL108399 | 0.82 | TSHR (0.44) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL108398 | 0.82 | TSHR (0.44) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL11601333 | 0.82 | TSHR (0.44) | TSHRALDH1A1GRIK1HPGDEP300 | |
| SCHEMBL29284385 | 0.78 | TSHR (0.43) | TSHRALDH1A1EP300 | |
| SCHEMBL29284373 | 0.78 | TSHR (0.43) | TSHRALDH1A1EP300 | |
| SCHEMBL8430984 | 0.77 | TSHR (0.39) | TSHRALDH1A1HPGDZDHHC20ZDHHC2 | |
| SCHEMBL8430987 | 0.77 | TSHR (0.39) | TSHRALDH1A1HPGDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562167-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |