Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430984 | 1.00 | TSHR (0.39) | TSHRALDH1A1TP53CES1HPGD | |
| SCHEMBL11601333 | 0.91 | TSHR (0.44) | TSHRALDH1A1TP53CES1HPGD | |
| SCHEMBL108399 | 0.91 | TSHR (0.44) | TSHRALDH1A1TP53CES1HPGD | |
| SCHEMBL108398 | 0.91 | TSHR (0.44) | TSHRALDH1A1TP53CES1HPGD | |
| SCHEMBL29284258 | 0.87 | TSHR (0.48) | TSHRTP53ZDHHC20ZDHHC2 | |
| SCHEMBL13594545 | 0.87 | ALDH1A1 (0.35) | TSHRALDH1A1LSS | |
| SCHEMBL16486617 | 0.86 | TSHR (0.39) | TSHRALDH1A1LSS | |
| SCHEMBL7114255 | 0.85 | TSHR (0.37) | TSHRALDH1A1TP53CES1HPGD | |
| SCHEMBL3645681 | 0.84 | ALDH1A1 (0.37) | TSHRALDH1A1TP53CES1HPGD | |
| SCHEMBL3645679 | 0.84 | ALDH1A1 (0.37) | TSHRALDH1A1TP53CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662323-B2 | Thermoplastic blend formulations for cable insulations | NKT HV CABLES AB (SE) | 2020-05-26 | — | — | US | disclosed |
| EP-3033391-B1 | THERMOPLASTIC BLEND FORMULATIONS FOR CABLE INSULATIONS | NKT HV CABLES GMBH (CH) | 2019-07-31 | — | — | EP | disclosed |
| US-20160194489-A1 | THERMOPLASTIC BLEND FORMULATIONS FOR CABLE INSULATIONS | ABB TECHNOLOGY LTD (CH) | 2016-07-07 | — | — | US | disclosed |
| EP-3033391-A1 | THERMOPLASTIC BLEND FORMULATIONS FOR CABLE INSULATIONS | ABB Technology Ltd. (CH) | 2016-06-22 | — | — | EP | disclosed |
| WO-2015022004-A1 | THERMOPLASTIC BLEND FORMULATIONS FOR CABLE INSULATIONS | ABB TECHNOLOGY LTD (CH) | 2015-02-19 | — | — | WO | disclosed |
| US-5929298-A | Process for preparing conjugated dienes using substituted rhenium trioxide | EASTMAN CHEMICAL COMPANY (US) | 1999-07-27 | — | — | US | disclosed |