Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 10/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730721 | 0.83 | USP30 (0.49) | PARP1USP30HDAC4HDAC6 | |
| SCHEMBL14730843 | 0.81 | KDM5A (0.38) | PARP1USP30CCNA2CDK2 | |
| SCHEMBL14730842 | 0.78 | PARP1 (0.46) | PARP1HDAC4CCNA2CDK2CDK5 | |
| SCHEMBL14730708 | 0.77 | USP30 (0.47) | PARP1USP30HDAC4HDAC6 | |
| SCHEMBL16248391 | 0.76 | USP30 (0.51) | PARP1USP30HDAC4HDAC6CCNA2 | |
| SCHEMBL14730841 | 0.76 | L3MBTL1 (0.40) | — | |
| SCHEMBL20029112 | 0.73 | USP30 (0.60) | PARP1USP30HDAC4HDAC6 | |
| SCHEMBL20029199 | 0.73 | USP30 (0.60) | PARP1USP30HDAC4HDAC6 | |
| SCHEMBL889095 | 0.69 | USP30 (0.55) | PARP1USP30HDAC4HDAC6CCNA2 | |
| SCHEMBL18124157 | 0.69 | USP30 (0.69) | PARP1USP30HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026163-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |