Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730796 | 0.90 | KDR (0.46) | JAK2KDRTLR8TLR7MAPKAPK2 | |
| SCHEMBL14730722 | 0.90 | KDR (0.46) | JAK2KDRTLR8TLR7MAPKAPK2 | |
| SCHEMBL14730766 | 0.85 | RAB9A (0.47) | JAK2KDRTLR9TLR8TLR7 | |
| SCHEMBL14730725 | 0.84 | RAB9A (0.47) | JAK2KDRTLR9TLR8TLR7 | |
| SCHEMBL16248395 | 0.84 | RAB9A (0.47) | JAK2KDRTLR9TLR8TLR7 | |
| SCHEMBL16248387 | 0.84 | RAB9A (0.47) | JAK2KDRTLR9TLR8TLR7 | |
| SCHEMBL14730798 | 0.82 | RAB9A (0.44) | JAK2KDRTLR9TLR8TLR7 | |
| SCHEMBL14730764 | 0.82 | RAB9A (0.49) | JAK2KDRTLR9TLR8TLR7 | |
| SCHEMBL14730703 | 0.82 | KDR (0.44) | JAK2KDRTLR8TLR7MAPKAPK2 | |
| SCHEMBL14730749 | 0.82 | KDR (0.44) | JAK2KDRTLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026163-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |